Bimatoprost and Tafluprost cause eyelash growth in rabbits
Curitiba – mechentel news – The results of the current study A.T. Giannio et al. from the Department of Veterinary Medicine, Federal University of Paraná, Curitiba, Brazil about eyelash Growth Induced by Topical Prostaglandin Analogues, Bimatoprost, Tafluprost, Travoprost, and Latanoprost in Rabbits showed that tafluprost could be further explored by the cosmetic and pharmaceutical industry. Prostaglandin analogues (PGA) are ocular hypotensive agents used for the treatment of glaucoma. Hypertrichosis of the eyelashes has been reported in humans as a side effect. Eyelash growth was investigated with clinical trials in people using bimatoprost. Scattered reports of eyelash growth during the treatment of glaucoma with other PGA are also found in the literature. The scientists investigated the effect of 4 different topical PGA on eyelash length. The Autors divided 14 New Zealand white rabbits into 4 groups receiving daily topical application of bimatoprost, tafluprost, travoprost, and latanoprost in the left eye for 4 weeks. The right eye received no treatment. Eyelash length was measured in both eyes before and after treatment using a stainless steel digital caliper. It is interesting to note that Bimatoprost and tafluprost groups had significant increases in eyelash length. The authors said in the August edition of the J Ocul Pharmacol Ther. “We did not observe significant eyelash growth in rabbits receiving travoprost and latanoprost after 1 month of treatment”.The authors conclude their study by saying that today, only bimatoprost is approved for growing eyelashes, and the research shows that additional research using travoprost and latanoprost as agents for eyelash growth should be performed in the future using prolonged treatment periods to determinate whether or not these PGA induce eyelash growth, and investigate other possible side effects.
Autoren: Giannico AT, Lima L, Russ HH, Montiani-Ferreira F. Korrespondenz: Department of Veterinary Medicine, Federal University of Paraná, Curitiba, Brazil. Studie: Eyelash Growth Induced by Topical Prostaglandin Analogues, Bimatoprost, Tafluprost, Travoprost, and Latanoprost in Rabbits. Quelle: Journal of Ocular Pharmacology and Therapeutics, 2013 Aug 27, doi: 10.1089/jop.2013.0075. http://online.liebertpub.com/doi/abs/10.1089/jop.2013.0075