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Fachverlag und Nachrichtenagentur

Autor: MZ

The pros and cons of vertebrate animal models for functional and therapeutic research on inherited retinal dystrophies.

Nijmegen – mechentel news – Over the last decade, huge progress has been made in the understanding of the molecular mechanisms underlying inherited retinal dystrophy (IRD), as well as in the development and implementation of novel therapies, especially in the field of gene therapy. The use of mutant animal models, either naturally occurring or generated by genetic modification, have contributed greatly to our knowledge on IRD. Yet, these mutant animal models do not always mimic the...

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Microscopic Lesions in Canine Eyes with Primary Glaucoma.

North Grafton – mechentel news – Although the clinical classification of primary glaucoma in dogs is quite simple, the phenotypes of glaucoma in most of the species are indeed multiple. Ophthalmologists can often evaluate the dynamic changes of clinical signs at different times in the course of the disease, whereas pathologists are often presented with globes that have undergone abundant therapies and are at the end stage. Therefore, an open collaboration between clinicians and pathologists...

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Ophthalmic variables in rehabilitated juvenile Kemp’s ridley sea turtles (Lepidochelys kempii)

North Grafton – mechentel news – To determine central corneal thickness (total corneal thickness [TCT], epithelial thickness [ET], and stromal thickness [ST]), anterior chamber depth (ACD), and intraocular pressure (IOP) in Kemp’s ridley sea turtles (Lepidochelys kempii), 25 healthy rehabilitated juvenile Kemp’s ridley sea turtles were enrolled in the prospective cross-sectional study. Body weight and straight-line standard carapace length (SCL) were recorded. All turtles...

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An association between systemic cyclosporine administration and development of acute bullous keratopathy in cats.

East Lansing – mechentel news – To determine whether any association exists between the onset of feline acute bullous keratopathy (ABK) and administration of systemic corticosteroid or immunosuppressive therapy, medical records of cats diagnosed with ABK between the years of 2000 and 2008 were retrospectively reviewed. Breed, age at diagnosis, weight, systemic disease status, eye affected, ophthalmic examination findings, systemic and topical therapy instituted, dosage and duration...

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